Fитнесс, ЗОЖ и красота
Аргинин. Реклама аргинина основана на заявлении, что он увеличивает уровень оксида азота, тем самым расширяет сосуды и увеличивает поток крови в мышцах (потому что он синтезируется из аргинина).
L-Arginine as a potential ergogenic aid in healthy subject...
L-arginine is claimed to promote vasodilation by increasing nitric oxide
(NO) production in the active muscle during exercise, improving
strength, power and muscular recovery through increased substrate
utilization and metabolite removal, such as lactate and ammonia.
Research on L-arginine has recently tested this hypothesis, under the
assumption that it may be the active compound associated with the
vasodilator effects of NO.
Кроме этого рассматривался вопрос влияния аргинина на пролиферацию сателлитных клеток, что обогащает миоциты новыми ядрами, что повышает их потенциал роста. Arginine supplementation induces myoblast fusion via augme.... Но это в пробирке. А вот in-vivo эффекты не доказаны:
The aim of this study was to investigate the ergogenic potential of arginine on NO synthesis, muscle blood flow, and skeletal muscle protein synthesis (MPS). Eight healthy young men (22.1 ± 2.6 y, 1.79 ± 0.06 m, 76.6 ± 6.2 kg; mean ± SD) participated in 2 trials where they performed a bout of unilateral leg resistance exercise and ingested a drink
containing either 10 g essential amino acids with 10 g l-arginine (ARG) or an isonitrogenous control (CON). Femoral artery blood flow of both the nonexercised and exercised leg was measured сontinuously using pulsed-wave Doppler ultrasound, while rates of mixed and myofibrillar MPS were determined using a primed continuous infusion of L-[ring-(13)C(6)] or L-[ring-(2)H(5)]phenylalanine. The plasma arginine concentration increased 300% during the ARG trial but not during the CON trial (P < 0.001). Plasma nitrate, nitrite, and endothelin-1, all markers of NO synthesis, did not change during either the ARG or CON trial. Plasma growth hormone increased to a greater degree after exercise in the ARG trial than CON trial (P < 0.05). Femoral artery blood flow increased 270% above basal
in the exercised leg (P < 0.001) but not in the nonexercised leg, with no differences between the ARG and CON trials. Mixed and myofibrillar MPS were both greater in the exercised leg compared with the nonexercised leg (P < 0.001), but did not differ between the ARG and CON treatments. We conclude that an oral bolus (10 g) of arginine does not increase NO synthesis or muscle blood flow. Furthermore, arginine does not enhance mixed or myofibrillar MPS either at rest or after resistance exercise beyond that achieved by feeding alone.
Ну вот не хочет аргинин в живом человеке повышать нитраты и нитриты. А с этим и все прочие эффекты идут лесом. Такие вот дела. Но вы кушайте его, кушайте. Производителю этих препаратов тоже ведь кушать хочется.
